Purpose: To identify patients likely to present with a vertebral compression fracture.

Rule:

Roman, et al.:
1. Age > 52 years
2. No presence of leg pain
3. Body mass index < 22
4. Does not exercise regularly
5. Female gender

Stage of CPR Development: Derivation.

Variables Sensitivity Specificity +LR -LR
1 0.97 0.06 1.04 0.39
2 0.95 0.34 1.40 0.16
3 0.76 0.68 2.50 0.34
4 0.37 0.96 9.60 0.65
5 0.03 0.99 9.30 0.97

Henschke, et al.:
1. Female sex
2. Age > 70 years old
3. Significant trauma (major in young patients, minor in elderly patients)
4. Prolonged use of corticosteroids

Stage of CPR Development: Derivation.

Variables Sensitivity Specificity +LR
1 0.88 0.50 1.8
2 0.63 0.96 15.5
3 0.38 1.00 218.3

Research:

1. Henschke N, Maher CG, Refshauge KM, Herbert RD, Cumming RG, Bleasel J, York J, Das A, McAuley JH. Prevalence of and Screening for Serious Spinal Pathology in Patients Presenting to Primary Care Settings With Acute Low Back Pain. Arthritis & Rheumatism. 2009; 60(10): 3072–3080.

2. Roman M, Brown C, Richardson W, Isaacs R, Howes C, Cook CE. The development of a clinical decision making algorithm for detection of osteoporotic vertebral compression fracture or wedge deformity. Journal of Manual and Manipulative Therapy. 2010; 18(1): 44-49.

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